Side Effects of Zoloft

Zoloft produces adverse effects which are more or less similar to the side effects of other antidepressants of the class SSRI. These side effects are explained in this article, along with the ones associated with zoloft withdrawal.
Zoloft, also known as 'sertraline' or sertraline hydrochloride is an antidepressant used for the treatment of major depression. Zoloft is actually the brand name for 'sertraline', and it belongs to the class of antidepressants, which are known as serotonin reuptake inhibitor (SSRI). It is basically indicated for the treatment of major depression, Obsessive Compulsive Disorder (OCD), Posttraumatic Stress Disorder (PTSD), panic disorders and social phobia or social anxiety conditions. It can be used for Premenstrual Dysphoric Disorder (PMDD) as well. Like other depression medications, Zoloft too can show a few side effects, although they are less pronounced as compared to that of tricyclic antidepressants.

Zoloft Complications

The side effects can vary to an extent from one individual to another. In general, its side effects are more or less similar to that of other drugs that belong to the class of serotonin reuptake inhibitor (SSRI). However unlike many other SSRIs, the effects of Zoloft on cognition are usually mild. The side effects that are more commonly observed in individuals using Zoloft are, nausea, diarrhea, insomnia, dry mouth, dizziness, ejaculation problems, headaches, drowsiness, decreased libido, loss of appetite, increased fatigue, indigestion and tremor.

Weight loss, increased sweating, abdominal pain and cramps, nervousness and hot flashes are some other common side effects. On the other hand, fever, incontinence, aggressive behavior, hyperactivity, sinus infection and red or purple discoloration on the skin are the common side effects in children. Side effects like, agitation, anxiety, changes in vision or blurred vision, redness of skin, flushing, increased appetite, vomiting, constipation, erectile dysfunction, hair loss, glaucoma, high blood pressure, muscle pain, menstrual problems, tinnitus or ringing in the ear, rhinitis, irregular heart rhythm, hallucinations and seizures are some of the less common and rare side effects associated with this medication.

Weight gain is another less common side effect that is not experienced by all individuals taking Zoloft. Weight gain is more commonly observed when Zoloft is used for a prolonged time period. Apart from these, Zoloft and other antidepressants may increase the risk of suicide in individuals younger than 25. overdose of Zoloft on the other hand, can cause vomiting, unsteady movement and gait, lethargy, tachycardia and seizures. Zoloft can also interact with certain medications like, Monoamine Oxidase Inhibitors (MAOI), cimetidine, pimozide and warfarin. If you are taking any of these drugs, then please inform your physician before using Zoloft.

Zoloft Withdrawal

Sudden discontinuation of this drug can also produce some uncomfortable withdrawal symptoms. The most common symptoms associated with its withdrawal are anxiety, agitation, irritability, nausea, headaches, muscle pain, tremor, hallucinations, insomnia, dizziness, confusion, vomiting, high grade fever and 'brain zap', which is usually defined as an electric shock or jolt like sensation. These symptoms can appear within a few days after reducing the dosage or complete withdrawal of Zoloft.

It is important to take it only in the prescribed dosage. People taking other drugs, especially monoamine oxidase inhibitors, cimetidine, pimozide and warfarin should let their physician know about it before taking Zoloft. Similarly, if you are suffering from an underlying medical condition, especially liver or kidney disease, bipolar disorder, seizures and epilepsy, then inform your physician about it. Lastly, if you observe any of the serious side effects such as, suicidal thoughts, anxiety, aggressiveness, unusual changes in behavior, excessive vomiting, nausea and diarrhea, high blood pressure, hallucinations, irregular heart rhythm, fever, tremor and seizures, then be sure to seek medical attention or talk to your physician immediately.
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Published: 9/15/2010
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