Rabies Symptoms in Humans

About a century ago, rabies was one of the most dreaded diseases that had no treatment and resulted in a slow, agonizing death. However, after the rabies vaccine was produced, developed countries have successfully controlled the condition. This article sheds light on rabies symptoms in humans and animals, as well as its treatment.
Rabies is a disease caused by rabies virus occurring primarily in animals both wild and domestic. The virus is transferred from infected animals to humans, usually through a bite. Though people usually associate rabies with dogs, it is also commonly seen in cats. Other animals such as horses, mules, sheep and goats are also known to be carriers of the disease. Among wild animals, the highest number of incidents are reported in skunks, raccoons, bats, foxes and rodents. Since the rabies virus exists in the saliva of an infected animal, it is usually transmitted when the animal bites or scratches a victim, causing their skin to puncture. The virus has a strong penchant for nervous system cells. It enters nerve cells at the site of the wound, from where it travels to the brain, and then spreads to muscles and organs by following other nerve pathways. Among the most well known symptoms of rabies in humans is the fear of water, or ‘Hydrophobia’. This fear manifests in the victims, leaving them terrified by the sight of water, and suffering severe pain while swallowing liquids even though they are very thirsty. As animals transmit the disease to humans, it is better to first study the symptoms of the disease in animals as this can act as a safeguard for humans.

Rabies Symptoms in Animals
Evidence of the rabies virus in animals is seen in behavioral changes and other noticeable signs. If you suspect an animal of having rabies, keep an eye out for telltale signs, so that timely preventive treatment to the person exposed can be provided. An animal that shows any of the following signs may have rabies:
  • A wild animal that does not display any signs of fear of humans, or acts aggressively
  • Unusual shyness in a domestic pet, restlessness, disorientation, excitability, aggression, or sudden mood changes
  • Excessive drooling and frothing at times
  • Animals that are normally active at night (such as bats, raccoons, and skunks) becoming active during the day
  • Infected animals eat substances they normally do not eat
  • Paralysis is sometimes the only sign
  • Change in a dogs bark
  • Dilated pupils
These symptoms are seen within the period of between 20 and 60 days after exposure. Rabid animals are known to become combative, aggressive, highly sensitive to touch or other kinds of stimulation. Development of this kind of viciousness is termed "furious" rabies. The condition does not always make its presence know in aggressive manner, and the quiet or "dumb" form of the disease leaves an animal lethargic, weak in one or more limbs, and unable to raise its head or make sounds because its throat and neck muscles are paralyzed. In both forms of the condition, death (usually from respiratory failure) takes place a few days after symptoms appear.

Rabies Symptoms in Humans
If a person is bitten by an animal suffering from rabies, the incubation period can stretch up to 2 to 3 months. In rare cases, it can extend to almost a year. During the incubation period, there are often no symptoms of rabies. Some of the early symptoms are acute pain or numbness at the site of the bite, followed by other symptoms which can be confused with symptoms of other common diseases. Some early symptoms of human rabies are:
  • Cough or sore throat at times accompanied with a running nose
  • Fever and severe headache
  • Itching, pain, tingling, burning, or numbness at the site of the bite/scratch
  • Abdominal pain
  • Anxiety or restlessness that slowly worsens and may become agitated behavior
Some of the later symptoms which are very distinctive with the ailment, are periods of normal behavior that alternate with bizarre behavior such as:
  • Extreme anxiety and an agitated attitude or depression
  • Hallucinations accompanied by unusual chatter
  • Delirium
  • Spasms of the muscles in the face, neck or stomach followed by seizures
  • Wide variations (fluctuations) in temperature, pulse and blood pressure
  • ‘Hydrophobia’, or fear of water
  • Paralysis associated with rabies is contracted when bitten by a vampire bat
  • Coma and/or heart and respiratory failure
Rabies Prevention

The best way to safeguard oneself is to ensure that one's pets are administered the rabies vaccine in a timely fashion. Preventive vaccines are available for dogs, cats, horses, cattle, and sheep, which are freely available and can be administered by a licensed veterinarian. All dogs and cats should be vaccinated first after 12 weeks of age, then one year later, followed by one every 3 years. People whose professions require them to have frequent contact with animals (e.g., pet groomers, zookeepers) must get a pre-exposure rabies vaccination. Others are advised against keeping skunks, foxes, raccoons, or bats as pets, as they cannot be vaccinated and are susceptible to rabies. Lastly, if you see any animal exhibiting abnormal behavior, such as a wild animal that seems friendly, be vary of it.

Rabies Treatment
If due to some unfortunate course of event, you do end up getting bitten by an animal, immediately wash the site of the injury thoroughly with soap. Following this, one must not wait for rabies symptoms in humans to develop, but seek immediate medical attention. If rabies vaccine treatment is required, the earlier it is started, the better. There was a time when a patient had to take a course of 7 to14 injections of rabies immune globulin (RIG), which were administered in the abdomen. However, thanks to modern science, the current vaccine usually involves only one or 3 intra-muscular injections.

By Marian K
Published: 8/12/2009
 
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