PSA Test Results Meaning

Elevated levels of PSA in the body indicates an increase in the risk of prostate disorders like cancer. The following article discusses PSA test results meaning and interpretation in short.
What is a PSA test? There is a small gland encircling the urethra in males. It is called prostate gland. It produces the fluid which makes up the semen. The cells of the prostate gland produce an antigen called prostate-specific antigen (PSA). Most of the PSA is secreted into the semen. Only a small amount of it is released into the bloodstream. The test which is done to measure the level of PSA in the bloodstream is called PSA test. It gives information about the prostate health. The data is used by the doctors as a marker for tumor and for screening and monitoring prostate disorders like cancer.

The level of PSA rises under certain conditions. A digital rectal examination (DRE) may cause a rise in the level of PSA. This is why, medical practitioners often conduct DRE test at the end, whenever it has to be performed. A biopsy may also increase the level of PSA in the blood. Other conditions which can bring a rise in the PSA level are strenuous exercise, chemotherapy drugs, some kind of medications and prostate infections. A knowledge of PSA test results meaning will always help you in taking good care of your health.

PSA Test Results Reading
PSA is measured in nanograms of PSA per milliliter of blood (ng/ml). The PSA result is compared against the normal ranges listed by the testing laboratory. The normal ranges usually differ from laboratory to laboratory and from doctor to doctor. Thus, a certain value may give a different possibility of the development of prostate disorders for different people.

A point worth mentioning here is that a PSA result alone is not diagnostic of prostate cancer. Generally, a PSA blood test is followed by a DRE, wherein the doctor examines the prostate structure to find out enlargements, tumors or swellings. If required, the doctor may carry out a prostate biopsy. The biopsy of normal or enlarged prostate involves removal of a small amount of tissue for testing. It is done to test suspicious findings. The result of PSA is often related with factors like age, drug consumption and data obtained from DRE and infection screen. The purpose is to find out if additional testing is required.

PSA Test Result Interpretation
A doctor is the best person who can accurately interpret the result of PSA test. There has been some disagreement among the medical professionals regarding the exact PSA test results meaning. However, according to majority of them, the normal value of PSA is 0.4 nanograms per milliliter of blood. If a person has PSA level anywhere between 4.0 and 10 nanograms per milliliter of blood, he is taken as having a 25 per cent increased danger of developing prostate cancer. In case, a person has a PSA level greater than 10 nanograms per milliliter of blood, he is at a higher than 65 per cent risk of developing prostate cancer.

But the above PSA test results meaning is not clear. Many-a-times, the doctors recommend an additional test called a "free PSA" to determine if the elevated PSA levels are "free PSA". A higher ratio of free PSA means a lower risk of prostate cancer. On the other hand, a lower ratio of free PSA indicates a higher possibility of prostate cancer. The doctors often observe the change in the concentration of PSA over a certain period of time. If the PSA level remains elevated for a period of 3-4 years, the person is likely to suffer from prostate cancer. The doctors may also take help of the data obtained from PSA test like velocity and density of PSA to find if the person is at a risk of developing some kind of prostate disorder.

The information given by the present article is what most of the medical practitioners believe. It may be different for different doctors. So, you should visit a doctor for understanding PSA test results with respect to your medical state.
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Published: 6/29/2010
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