Drosophila Melanogaster Life Cycle
Drosophila melanogaster life cycle comprises four successive stages, namely, egg, larva, pupa and adult. Leaf through this article to understand the life cycle of Drosophila melanogaster.

From the estimated 6 - 10 millionth insect species, Drosophila melanogaster is widely used as a model organism in biology experiments. It is studied as a representing organism of eukaryotes. Be it in evolution, genetics, developmental biology or pathology, fruit fly is used in several fields of science. So, what is so particular about this flying insect? Well, the specialty of fruit fly lies in its short life cycle, easy breeding and production of large offspring (a female fruit fly lays about 100 eggs per day).
Fruit Fly (Drosophila melanogaster): Life Cycle
In laboratory studies, a new generation of fruit flies can be obtained after every two weeks. With the advancement in genetic research, sequencing the genome of Drosophila is completed and issued in the year 2000. Besides the small body size, there are only 4 pairs of chromosomes. Also, a lot of D. melanogaster mutant forms are produced and identified with different names. If you are a science student, you may be well acquainted with the life cycle of Drosophila melanogaster.
The length of developing time (an egg maturing into an adult) varies with respect to the prevailing temperature, which is a characteristic of all cold-blooded insects. When kept in room temperature (77° F), a Drosophila egg requires 8.5 days to develop into an adult; whereas in temperatures higher than this, development time is more because of heat stress. The life cycle stages of D. melanogaster along with their associated features are discussed below:
Egg: The egg of Drosophila melanogaster is about 0.5 mm. A female may lay as many as 400 eggs in a favorable egg laying ground (for example, a decaying mushroom or fruit). Within 24 hours of laying, the eggs hatch into 1st instar larvae. In room temperature conditions, this hatching time is as short as 15 hours.
Larva: The larval stage of D. consists of three instars. Within 24 hours of hatching, the larva molts to develop into 2nd instar larva. Again after 24 hours (i.e. 48 hours after egg hatching), the 2nd instar larva molts and matures to 3rd instar larva. During these molting stages, the larva loses its spiracles, mouth and hooks.
Pupa: After 4 days of voracious feeding, the 3rd instar larva encapsulates itself inside a hard and dark-colored puparium. It is in this pupal stage, where the metamorphosis of D. melanogaster takes place, giving rise to wings and legs. In room temperature condition, the duration of metamorphosis lasts for 4 days.
Adult: The adult D. melanogaster emerges through the operculum of the puparium. And within 8 - 12 hours of emergence, the female fly is receptive. Then, it mates with the male Drosophila for about 30 minutes, during which the male inseminates a few hundreds of sperms in the female fly. The female Drosophila stores the sperms and uses them latter for laying eggs.
So, isn't Drosophila melanogaster life cycle interesting to study? Since the maturation time of fruit flies differs with temperature fluctuation, it is obvious that their life span or longevity also varies with the surrounding environmental conditions. In general, the lifespan of Drosophila lasts for several weeks. And, considering the ease of breeding and caring, scientists all over the world agree that fruit flies will remain to be the most versatile model organism in biological science.
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