Coenzyme Q10 Supplement

Are you looking for information on Coenzyme Q10 supplements? This article will help you understand the uses and forms of these supplements as well as discuss the pros and cons of its use.
Coenzyme Q10, also called ubiquinone, is a 1,4 benzoquinone, which occurs naturally within the body and is found primarily in the mitochondria of eukaryotic cells. It is used for the production of Adenosine Triphosphate (ATP) and is important for the process of aerobic respiration on the cellular level. An enzyme is composed of two parts - one of which is a protein, and the other, either a vitamin or a mineral; an enzyme made up of a protein and a vitamin, is called a Coenzyme. Coenzyme Q10, or CoQ10 as it is commonly known, is also found in certain foods like sardines, salmon, mackerel, olive oil, grape seed oil, soybean oil, blackberries, strawberries, hazelnuts, avocado, walnuts and spinach; however, it is also produced synthetically in the form of supplements. There is a good deal of controversy surrounding the use of these supplements, since there exists mixed evidence displaying the benefits of CoQ10. Having said that, the following is the medical evidence gathered so far.

Benefits
There are however, a number of benefits associated with CoQ10 supplements as treatments. They are antioxidants and are believed to contribute to an increase in energy levels, owing to their role of developing the energy rich ATP in the body. Coenzyme Q10 is also used for the treatment of a number of diseases, like Parkinson's Disease, diabetes and high blood pressure. In addition it is also prescribed for:
  • Periodontal Diseases
  • Cardiomyopathy
  • Cancer
  • Migraines
  • Kidney Diseases
Side Effects
As mentioned earlier however, there is insufficient medical evidence to display that CoQ10 is beneficial as a health supplement and a good deal of controversy surrounds the practice of prescribing it as a course of treatment - this is supported by the many side effects exhibited. Statins are found to have a lowering effect on CoQ10 levels within the body, because of their tendency to inhibit the production of mevalonate, required for the production of Coenzyme Q10. As a result of this, supplements are sometimes prescribed to people who suffer from high cholesterol and are prescribed statins as treatment. Although CoQ10 benefits do exist, even the best supplements are associated with a number of side effects, listed as follows. In addition, there is also some evidence to suggest that CoQ10 supplements can reduce the body's response to blood thinners and anticoagulants.
  • Mild insomnia
  • Rashes
  • Upper abdominal pain
  • Nausea
  • Headache
  • Heartburn
  • Fatigue
  • Sensitivity to light
  • Irritability
Dosage
Despite the controversy surrounding it, Coenzyme Q10 is widely available as a health supplement. It is thought that given the role of CoQ10 in the production of energy, boosting its levels by dietary supplements can have a beneficial effect especially on the energy levels of moderate to heavy exercisers. Typically, dosage of supplements ranges between 30mg and 90 mg, divided over the course of the day, instead of ingested at a go. Some studies have indicated that being a fat soluble substance, its benefits are enhanced when taken with a meal containing fats, oils, or fatty acids.

When taking dietary supplements, it is important to discuss the pros and cons with a qualified health practitioner, who will assist you in making an informed choice. This is particularly important if you are already on other drugs and medications, which may be hampered in their functioning, or have an adverse effect on you. In addition, a lot of supplements may come along with a host of side effects which belie the benefits they claim to cause. Until such time that there is conclusive evidence to support the use of Coenzyme Q10 supplements, it may be wise to avoid taking them in artificial form. Raise the levels of foods containing this Coenzyme in your diet to ensure a healthy option, and enjoy the benefits without the hazards.
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Published: 8/27/2010
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